increased leukemia incidence_Kmt2a<tm1Saam>/Kmt2a<+>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0002026I129S1SvC57BL6CBAKmt2atm1SaamKmt2aTgMx1cre1Cgn0TgMx1cre1CgnKmt2aKmt2atm1Saam

increased leukemia incidence_Kmt2a<tm1Saam>/Kmt2a<+>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• lysine (K)-specific methyltransferase 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:96995

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kmt2a<tm1Saam>/Kmt2a<+>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)1Cgn|Kmt2a<+>|Kmt2a<tm1Saam>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased leukemia incidence
  http://purl.obolibrary.org/obo/MP_0002026

文献

http://purl.org/net/cito/citesAsAuthority

• Andrei V. Krivtsov, et.al., H3K79 methylation profiles define murine and human MLL-AF4 leukemias., Cancer cell, 2008, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/18977325