increased leukemia incidence_Rac3<tm1Hkp>/Rac3<tm1Hkp>,Tg(BCR/ABL)623Hkp/0

http://metadb.riken.jp/0002026IC57BL6C57BL6JCBARac3tm1HkpRac3tm1HkpTgBCRABL623Hkp0Rac3tm1HkpTgBCRABL623Hkp

increased leukemia incidence_Rac3<tm1Hkp>/Rac3<tm1Hkp>,Tg(BCR/ABL)623Hkp/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 623, Nora Heisterkamp
  http://metadb.riken.jp/db/mgi_rdf/MGI:3582387
• RAS-related C3 botulinum substrate 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:2180784

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rac3<tm1Hkp>/Rac3<tm1Hkp>,Tg(BCR/ABL)623Hkp/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rac3<tm1Hkp>|Tg(BCR/ABL)623Hkp

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6J * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased leukemia incidence
  http://purl.obolibrary.org/obo/MP_0002026

文献

http://purl.org/net/cito/citesAsAuthority

• Young Jin. Cho, et.al., Generation of rac3 null mutant mice: role of Rac3 in Bcr/Abl-caused lymphoblastic leukemia., Molecular and cellular biology, 2005, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/15964830