increased lung adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>

http://metadb.riken.jp/0002027I129S4SvJaeKrastm4TyjKrasTrp53tm2TyjTrp53Trp53tm2TyjTrp53KrasKrastm4Tyj

increased lung adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Trp53<tm2Tyj>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm2Tyj>|Trp53<+>|Kras<+>|Kras<tm4Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0002027

文献

http://purl.org/net/cito/citesAsAuthority

• Andrea L. Kasinski, et.al., miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma., Cancer research, 2012, 72
  http://rdf.ncbi.nlm.nih.gov/pubmed/22964582