increased lung adenocarcinoma incidence_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-EGFR*L858R)57Hev/0

http://metadb.riken.jp/0002027IC57BL6CBATgScgb1a1rtTA1Jaw0TgtetOEGFRL858R57Hev0TgScgb1a1rtTA1JawTgtetOEGFRL858R57Hev

increased lung adenocarcinoma incidence_Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-EGFR*L858R)57Hev/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 57, Harold E Varmus
  http://metadb.riken.jp/db/mgi_rdf/MGI:3690073
• transgene insertion 1, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:2652186

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Scgb1a1-rtTA)1Jaw/0,Tg(tetO-EGFR*L858R)57Hev/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Scgb1a1-rtTA)1Jaw|Tg(tetO-EGFR*L858R)57Hev

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0002027

文献

http://purl.org/net/cito/citesAsAuthority

• Katerina. Politi, et.al., Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors., Genes & development, 2006, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/16705038