increased sarcoma incidence_Rnf168<Gt(156B6)Cmhd>/Rnf168<Gt(156B6)Cmhd>,Trp53<tm1Brd>/Trp53<tm1Brd>

http://metadb.riken.jp/0002032I129S1Sv129S7SvEvBrd129X1SvJC57BL6Rnf168Gt156B6CmhdRnf168Gt156B6CmhdTrp53tm1BrdTrp53tm1BrdTrp53tm1BrdRnf168Gt156B6Cmhd

increased sarcoma incidence_Rnf168<Gt(156B6)Cmhd>/Rnf168<Gt(156B6)Cmhd>,Trp53<tm1Brd>/Trp53<tm1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ring finger protein 168
  http://metadb.riken.jp/db/mgi_rdf/MGI:1917488
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rnf168<Gt(156B6)Cmhd>/Rnf168<Gt(156B6)Cmhd>,Trp53<tm1Brd>/Trp53<tm1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brd>|Rnf168<Gt(156B6)Cmhd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased sarcoma incidence
  http://purl.obolibrary.org/obo/MP_0002032

文献

http://purl.org/net/cito/citesAsAuthority

• Toshiyuki. Bohgaki, et.al., Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome., PLoS genetics, 2011, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/21552324