increased sarcoma incidence_Cdkn2a<tm1Cjs>/Cdkn2a<tm1Cjs>,Pax7<tm1Pgr>/Pax7<+>,Tg(CKMM-tTA)A3Rhvh/0,Tg(tetO-Hgf,-EGFP)24Tcre/0

http://metadb.riken.jp/0002032I129S2SvPas129X1SvJFVBCdkn2atm1CjsCdkn2atm1CjsPax7tm1PgrPax7TgCKMMtTAA3Rhvh0TgtetOHgfEGFP24Tcre0Cdkn2atm1CjsPax7Pax7tm1PgrTgCKMMtTAA3RhvhTgtetOHgfEGFP24Tcre

increased sarcoma incidence_Cdkn2a<tm1Cjs>/Cdkn2a<tm1Cjs>,Pax7<tm1Pgr>/Pax7<+>,Tg(CKMM-tTA)A3Rhvh/0,Tg(tetO-Hgf,-EGFP)24Tcre/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738
• transgene insertion 24, Tiziana Crepaldi
  http://metadb.riken.jp/db/mgi_rdf/MGI:5648117
• paired box 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:97491
• transgene insertion A3, R Hooft van Huijsduijnen
  http://metadb.riken.jp/db/mgi_rdf/MGI:3621121

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Cjs>/Cdkn2a<tm1Cjs>,Pax7<tm1Pgr>/Pax7<+>,Tg(CKMM-tTA)A3Rhvh/0,Tg(tetO-Hgf,-EGFP)24Tcre/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2a<tm1Cjs>|Pax7<+>|Pax7<tm1Pgr>|Tg(CKMM-tTA)A3Rhvh|Tg(tetO-Hgf,-EGFP)24Tcre

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129X1/SvJ * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased sarcoma incidence
  http://purl.obolibrary.org/obo/MP_0002032

文献

http://purl.org/net/cito/citesAsAuthority

• Deborah. Morena, et.al., Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes., eLife, 2016, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/26987019