increased rhabdomyosarcoma incidence_Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Myf6<tm1(cre)Mrc>/Myf6<+>,Pax3<tm1Mrc>/Pax3<tm1Mrc>

http://metadb.riken.jp/0002036I129S1Sv129X1SvJC57BL6SJLCdkn2atm4RdpCdkn2atm4RdpMyf6tm1creMrcMyf6Pax3tm1MrcPax3tm1MrcMyf6tm1creMrcPax3tm1MrcCdkn2atm4RdpMyf6

increased rhabdomyosarcoma incidence_Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Myf6<tm1(cre)Mrc>/Myf6<+>,Pax3<tm1Mrc>/Pax3<tm1Mrc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• paired box 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:97487
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738
• myogenic factor 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:97253

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Myf6<tm1(cre)Mrc>/Myf6<+>,Pax3<tm1Mrc>/Pax3<tm1Mrc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Myf6<tm1(cre)Mrc>|Pax3<tm1Mrc>|Cdkn2a<tm4Rdp>|Myf6<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased rhabdomyosarcoma incidence
  http://purl.obolibrary.org/obo/MP_0002036

文献

http://purl.org/net/cito/citesAsAuthority

• Charles. Keller, et.al., Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function., Genes & development, 2004, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/15489287