increased rhabdomyosarcoma incidence_Fos<tm1Wag>/Fos<tm1Wag>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

http://metadb.riken.jp/0002036I129S2SvPasC57BL6Fostm1WagFostm1WagTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjFostm1Wag

increased rhabdomyosarcoma incidence_Fos<tm1Wag>/Fos<tm1Wag>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• FBJ osteosarcoma oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:95574

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fos<tm1Wag>/Fos<tm1Wag>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Tyj>|Fos<tm1Wag>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased rhabdomyosarcoma incidence
  http://purl.obolibrary.org/obo/MP_0002036

文献

http://purl.org/net/cito/citesAsAuthority

• Alexander. Fleischmann, et.al., Rhabdomyosarcoma development in mice lacking Trp53 and Fos: tumor suppression by the Fos protooncogene., Cancer cell, 2003, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/14706339