increased rhabdomyosarcoma incidence_Cdkn2a<tm1Cjs>/Cdkn2a<+>,Tg(CKMM-tTA)A3Rhvh/0,Tg(tetO-Hgf,-EGFP)24Tcre/0

http://metadb.riken.jp/0002036I129X1SvJFVBCdkn2atm1CjsCdkn2aTgCKMMtTAA3Rhvh0TgtetOHgfEGFP24Tcre0TgtetOHgfEGFP24TcreTgCKMMtTAA3RhvhCdkn2aCdkn2atm1Cjs

increased rhabdomyosarcoma incidence_Cdkn2a<tm1Cjs>/Cdkn2a<+>,Tg(CKMM-tTA)A3Rhvh/0,Tg(tetO-Hgf,-EGFP)24Tcre/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738
• transgene insertion 24, Tiziana Crepaldi
  http://metadb.riken.jp/db/mgi_rdf/MGI:5648117
• transgene insertion A3, R Hooft van Huijsduijnen
  http://metadb.riken.jp/db/mgi_rdf/MGI:3621121

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Cjs>/Cdkn2a<+>,Tg(CKMM-tTA)A3Rhvh/0,Tg(tetO-Hgf,-EGFP)24Tcre/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-Hgf,-EGFP)24Tcre|Tg(CKMM-tTA)A3Rhvh|Cdkn2a<+>|Cdkn2a<tm1Cjs>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased rhabdomyosarcoma incidence
  http://purl.obolibrary.org/obo/MP_0002036

文献

http://purl.org/net/cito/citesAsAuthority

• Deborah. Morena, et.al., Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes., eLife, 2016, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/26987019