increased carcinoma incidence_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Csnk1a1<tm1.1Ybn>/Csnk1a1<tm1.1Ybn>,Tg(Vil-cre/ERT2)23Syr/0

http://metadb.riken.jp/0002038I129C57BL6CD1DBA2Cdkn1atm1TyjCdkn1atm1TyjCsnk1a1tm11YbnCsnk1a1tm11YbnTgVilcreERT223Syr0TgVilcreERT223SyrCsnk1a1tm11YbnCdkn1atm1Tyj

increased carcinoma incidence_Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Csnk1a1<tm1.1Ybn>/Csnk1a1<tm1.1Ybn>,Tg(Vil-cre/ERT2)23Syr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• casein kinase 1, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1934950
• transgene insertion 23, Sylvie Robine
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053810
• cyclin-dependent kinase inhibitor 1A (P21)
  http://metadb.riken.jp/db/mgi_rdf/MGI:104556

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>,Csnk1a1<tm1.1Ybn>/Csnk1a1<tm1.1Ybn>,Tg(Vil-cre/ERT2)23Syr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vil-cre/ERT2)23Syr|Csnk1a1<tm1.1Ybn>|Cdkn1a<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CD-1 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0002038

文献

http://purl.org/net/cito/citesAsAuthority

• Ela. Elyada, et.al., CKIα ablation highlights a critical role for p53 in invasiveness control., Nature, 2011, 470
  http://rdf.ncbi.nlm.nih.gov/pubmed/21331045