increased carcinoma incidence_Csnk1a1<tm1.1Ybn>/Csnk1a1<+>,Tg(Vil-cre/ERT2)23Syr/0,Trp53<tm1Brn>/Trp53<tm1Brn>

http://metadb.riken.jp/0002038I129C57BL6CD1DBA2Csnk1a1tm11YbnCsnk1a1TgVilcreERT223Syr0Trp53tm1BrnTrp53tm1BrnTgVilcreERT223SyrCsnk1a1tm11YbnTrp53tm1BrnCsnk1a1

increased carcinoma incidence_Csnk1a1<tm1.1Ybn>/Csnk1a1<+>,Tg(Vil-cre/ERT2)23Syr/0,Trp53<tm1Brn>/Trp53<tm1Brn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 23, Sylvie Robine
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053810
• casein kinase 1, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1934950

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Csnk1a1<tm1.1Ybn>/Csnk1a1<+>,Tg(Vil-cre/ERT2)23Syr/0,Trp53<tm1Brn>/Trp53<tm1Brn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vil-cre/ERT2)23Syr|Csnk1a1<tm1.1Ybn>|Trp53<tm1Brn>|Csnk1a1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CD-1 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0002038

文献

http://purl.org/net/cito/citesAsAuthority

• Ela. Elyada, et.al., CKIα ablation highlights a critical role for p53 in invasiveness control., Nature, 2011, 470
  http://rdf.ncbi.nlm.nih.gov/pubmed/21331045