increased neuroblastoma incidence_Alk<tm1.1Ics>/?,Tg(Th-MYCN)41Waw/0

http://metadb.riken.jp/0002039I129S2SvPas129X1SvJBALBcC57BL6C57BL6JAlktm11IcsTgThMYCN41Waw0TgThMYCN41WawAlktm11Ics

increased neuroblastoma incidence_Alk<tm1.1Ics>/?,Tg(Th-MYCN)41Waw/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• anaplastic lymphoma kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:103305
• transgene insertion 41, William A Weiss
  http://metadb.riken.jp/db/mgi_rdf/MGI:2673317

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Alk<tm1.1Ics>/?,Tg(Th-MYCN)41Waw/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Th-MYCN)41Waw|Alk<tm1.1Ics>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129X1/SvJ * BALB/c * C57BL/6 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased neuroblastoma incidence
  http://purl.obolibrary.org/obo/MP_0002039

文献

http://purl.org/net/cito/citesAsAuthority

• Alex. Cazes, et.al., Activated Alk triggers prolonged neurogenesis and Ret upregulation providing a therapeutic target in ALK-mutated neuroblastoma., Oncotarget, 2014, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/24811913