increased neuroblastoma incidence_Tg(Th-ALK*F1174L)2Loch/0,Tg(Th-MYCN)41Waw/0

http://metadb.riken.jp/0002039I129X1SvJBALBcC57BL6JCBATgThALKF1174L2Loch0TgThMYCN41Waw0TgThMYCN41WawTgThALKF1174L2Loch

increased neuroblastoma incidence_Tg(Th-ALK*F1174L)2Loch/0,Tg(Th-MYCN)41Waw/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 41, William A Weiss
  http://metadb.riken.jp/db/mgi_rdf/MGI:2673317
• transgene insertion 2, Louis Chesler
  http://metadb.riken.jp/db/mgi_rdf/MGI:5636484

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Th-ALK*F1174L)2Loch/0,Tg(Th-MYCN)41Waw/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Th-MYCN)41Waw|Tg(Th-ALK*F1174L)2Loch

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * BALB/c * C57BL/6J * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased neuroblastoma incidence
  http://purl.obolibrary.org/obo/MP_0002039

文献

http://purl.org/net/cito/citesAsAuthority

• Teeara. Berry, et.al., The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma., Cancer cell, 2012, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/22789543