increased pituitary adenoma incidence_Pomc<tm1Low>/Pomc<+>,Tg(Pomc)#Low/0

http://metadb.riken.jp/0002041I129C57BL6CBADBA2SwissWebsterPomctm1LowPomcTgPomcLow0Pomctm1LowPomcTgPomcLow

increased pituitary adenoma incidence_Pomc<tm1Low>/Pomc<+>,Tg(Pomc)#Low/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• pro-opiomelanocortin-alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:97742
• transgene insertion, Malcolm J Low
  http://metadb.riken.jp/db/mgi_rdf/MGI:4833832

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pomc<tm1Low>/Pomc<+>,Tg(Pomc)#Low/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pomc<tm1Low>|Pomc<+>|Tg(Pomc)#Low

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CBA * DBA/2 * Swiss Webster

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pituitary adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002041

文献

http://purl.org/net/cito/citesAsAuthority

• James L. Smart, et.al., Central dysregulation of the hypothalamic-pituitary-adrenal axis in neuron-specific proopiomelanocortin-deficient mice., Endocrinology, 2007, 148
  http://rdf.ncbi.nlm.nih.gov/pubmed/17095588