increased pituitary adenoma incidence_Pomc<tm1Low>/Pomc<+>

http://metadb.riken.jp/0002041I129S2SvPas129X1SvJC57BL6DBA2Pomctm1LowPomcPomcPomctm1Low

increased pituitary adenoma incidence_Pomc<tm1Low>/Pomc<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• pro-opiomelanocortin-alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:97742

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pomc<tm1Low>/Pomc<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pomc<+>|Pomc<tm1Low>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pituitary adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002041

文献

http://purl.org/net/cito/citesAsAuthority

• James L. Smart, et.al., Central dysregulation of the hypothalamic-pituitary-adrenal axis in neuron-specific proopiomelanocortin-deficient mice., Endocrinology, 2007, 148
  http://rdf.ncbi.nlm.nih.gov/pubmed/17095588