increased pituitary adenoma incidence_Thrb<tm1.1Syc>/Thrb<tm1.1Syc>

http://metadb.riken.jp/0002041I129S6SvEvTac129X1SvJC57BL6Thrbtm11SycThrbtm11SycThrbtm11Syc

increased pituitary adenoma incidence_Thrb<tm1.1Syc>/Thrb<tm1.1Syc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• thyroid hormone receptor beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:98743

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Thrb<tm1.1Syc>/Thrb<tm1.1Syc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Thrb<tm1.1Syc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pituitary adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002041

文献

http://purl.org/net/cito/citesAsAuthority

• Hiroko. Furumoto, et.al., An unliganded thyroid hormone beta receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis., Molecular and cellular biology, 2005, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/15601836