increased colonic adenoma incidence_Apc<tm2Rak>/Apc<tm2Rak>,Kras<tm4Tyj>/Kras<+>

http://metadb.riken.jp/0002044I129129S4SvJaeC57BL6JSJLApctm2RakApctm2RakKrastm4TyjKrasApctm2RakKrastm4TyjKras

increased colonic adenoma incidence_Apc<tm2Rak>/Apc<tm2Rak>,Kras<tm4Tyj>/Kras<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<tm2Rak>/Apc<tm2Rak>,Kras<tm4Tyj>/Kras<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apc<tm2Rak>|Kras<tm4Tyj>|Kras<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S4/SvJae * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased colonic adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002044

文献

http://purl.org/net/cito/citesAsAuthority

• Kenneth E. Hung, et.al., Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20080688