increased lung adenoma incidence_Msh2<tm1Mak>/Msh2<tm1Mak>,Mutyh<tm1Jhmi>/Mutyh<tm1Jhmi>,Ogg1<tm1Tld>/Ogg1<tm1Tld>

http://metadb.riken.jp/0002048I129C57BL6JMsh2tm1MakMsh2tm1MakMutyhtm1JhmiMutyhtm1JhmiOgg1tm1TldOgg1tm1TldMsh2tm1MakOgg1tm1TldMutyhtm1Jhmi

increased lung adenoma incidence_Msh2<tm1Mak>/Msh2<tm1Mak>,Mutyh<tm1Jhmi>/Mutyh<tm1Jhmi>,Ogg1<tm1Tld>/Ogg1<tm1Tld>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mutY DNA glycosylase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1917853
• 8-oxoguanine DNA-glycosylase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1097693
• mutS homolog 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:101816

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Msh2<tm1Mak>/Msh2<tm1Mak>,Mutyh<tm1Jhmi>/Mutyh<tm1Jhmi>,Ogg1<tm1Tld>/Ogg1<tm1Tld>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Msh2<tm1Mak>|Ogg1<tm1Tld>|Mutyh<tm1Jhmi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002048

文献

http://purl.org/net/cito/citesAsAuthority

• Yali. Xie, et.al., Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors., Cancer research, 2004, 64
  http://rdf.ncbi.nlm.nih.gov/pubmed/15126346