increased lung adenoma incidence_Fntb<tm1Bbd>/Fntb<tm1Bbd>,Kras<tm1Bbd>/Kras<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>

http://metadb.riken.jp/0002048I129S1Sv129X1SvJC57BL6CD1SJLFntbtm1BbdFntbtm1BbdKrastm1BbdKrasPolr2atm1creERT2BbdPolr2atm1creERT2BbdKrasFntbtm1BbdPolr2atm1creERT2BbdKrastm1Bbd

increased lung adenoma incidence_Fntb<tm1Bbd>/Fntb<tm1Bbd>,Kras<tm1Bbd>/Kras<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• polymerase (RNA) II (DNA directed) polypeptide A
  http://metadb.riken.jp/db/mgi_rdf/MGI:98086
• farnesyltransferase, CAAX box, beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:1861305

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fntb<tm1Bbd>/Fntb<tm1Bbd>,Kras<tm1Bbd>/Kras<+>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<+>|Fntb<tm1Bbd>|Polr2a<tm1(cre/ERT2)Bbd>|Kras<tm1Bbd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002048

文献

http://purl.org/net/cito/citesAsAuthority

• Nieves. Mijimolle, et.al., Protein farnesyltransferase in embryogenesis, adult homeostasis, and tumor development., Cancer cell, 2005, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/15837621