increased lung adenoma incidence_Kras<tm4Tyj>/Kras<+>,Mapkapk2<tm1.1Yaff>/Mapkapk2<tm1.1Yaff>

http://metadb.riken.jp/0002048I129S4SvJaeC57BL6Krastm4TyjKrasMapkapk2tm11YaffMapkapk2tm11YaffMapkapk2tm11YaffKrasKrastm4Tyj

increased lung adenoma incidence_Kras<tm4Tyj>/Kras<+>,Mapkapk2<tm1.1Yaff>/Mapkapk2<tm1.1Yaff>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• MAP kinase-activated protein kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109298
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Mapkapk2<tm1.1Yaff>/Mapkapk2<tm1.1Yaff>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mapkapk2<tm1.1Yaff>|Kras<+>|Kras<tm4Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased lung adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002048

文献

http://purl.org/net/cito/citesAsAuthority

• Sandra. Morandell, et.al., A reversible gene-targeting strategy identifies synthetic lethal interactions between MK2 and p53 in the DNA damage response in vivo., Cell reports, 2013, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/24239348