increased pheochromocytoma incidence_Pten<tm1Mro>/Pten<tm1Mro>,Sdhb<tm1.1Ics>/Sdhb<+>,Tg(KLK3-cre)D4Trp/0

http://metadb.riken.jp/0002050I129S2SvPasFVBPtentm1MroPtentm1MroSdhbtm11IcsSdhbTgKLK3creD4Trp0TgKLK3creD4TrpSdhbtm11IcsPtentm1MroSdhb

increased pheochromocytoma incidence_Pten<tm1Mro>/Pten<tm1Mro>,Sdhb<tm1.1Ics>/Sdhb<+>,Tg(KLK3-cre)D4Trp/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1914930
• transgene insertion D4, Jan Trapman
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761847

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Mro>/Pten<tm1Mro>,Sdhb<tm1.1Ics>/Sdhb<+>,Tg(KLK3-cre)D4Trp/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(KLK3-cre)D4Trp|Sdhb<tm1.1Ics>|Pten<tm1Mro>|Sdhb<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pheochromocytoma incidence
  http://purl.obolibrary.org/obo/MP_0002050

文献

http://purl.org/net/cito/citesAsAuthority

• Charlotte. Lepoutre-Lussey, et.al., From Nf1 to Sdhb knockout: Successes and failures in the quest for animal models of pheochromocytoma., Molecular and cellular endocrinology, 2016, 421
  http://rdf.ncbi.nlm.nih.gov/pubmed/26123588