increased skin papilloma incidence_Fgfr3<tm4Cxd>/Fgfr3<+>,Kras<tm4Tyj>/Kras<+>,Tg(Upk2-cre)6Xrw/0

http://metadb.riken.jp/0002051I129S4SvJae129S6SvEvTacFVBNFgfr3tm4CxdFgfr3Krastm4TyjKrasTgUpk2cre6Xrw0Fgfr3tm4CxdTgUpk2cre6XrwKrasFgfr3Krastm4Tyj

increased skin papilloma incidence_Fgfr3<tm4Cxd>/Fgfr3<+>,Kras<tm4Tyj>/Kras<+>,Tg(Upk2-cre)6Xrw/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• fibroblast growth factor receptor 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:95524
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• transgene insertion 6, Xue-Ru Wu
  http://metadb.riken.jp/db/mgi_rdf/MGI:3583892

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fgfr3<tm4Cxd>/Fgfr3<+>,Kras<tm4Tyj>/Kras<+>,Tg(Upk2-cre)6Xrw/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fgfr3<tm4Cxd>|Tg(Upk2-cre)6Xrw|Kras<+>|Fgfr3<+>|Kras<tm4Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S6/SvEvTac * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased skin papilloma incidence
  http://purl.obolibrary.org/obo/MP_0002051

文献

http://purl.org/net/cito/citesAsAuthority

• Imran. Ahmad, et.al., K-Ras and β-catenin mutations cooperate with Fgfr3 mutations in mice to promote tumorigenesis in the skin and lung, but not in the bladder., Disease models & mechanisms, 2011, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/21504907