decreased tumor incidence_Pten<tm1Rps>/Pten<+>,Rictor<Gt(RRR347)Byg>/Rictor<+>

http://metadb.riken.jp/0002052I129P2OlaHsd129S1SvBALBcC57BL6Ptentm1RpsPtenRictorGtRRR347BygRictorRictorGtRRR347BygPtentm1RpsPtenRictor

decreased tumor incidence_Pten<tm1Rps>/Pten<+>,Rictor<Gt(RRR347)Byg>/Rictor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• RPTOR independent companion of MTOR, complex 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926007

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Rps>/Pten<+>,Rictor<Gt(RRR347)Byg>/Rictor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rictor<Gt(RRR347)Byg>|Pten<tm1Rps>|Pten<+>|Rictor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002052

文献

http://purl.org/net/cito/citesAsAuthority

• David A. Guertin, et.al., mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice., Cancer cell, 2009, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/19185849