decreased tumor incidence_Eif4e<tm1.1Lfur>/Eif4e<tm1.1Lfur>,Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(Pbsn-cre)4Prb/0

http://metadb.riken.jp/0002052I129S1Sv129X1SvJC57BL6DBA2Eif4etm11LfurEif4etm11LfurPtentm21PppPtentm21PppTgPbsncre4Prb0Ptentm21PppTgPbsncre4PrbEif4etm11Lfur

decreased tumor incidence_Eif4e<tm1.1Lfur>/Eif4e<tm1.1Lfur>,Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(Pbsn-cre)4Prb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• eukaryotic translation initiation factor 4E
  http://metadb.riken.jp/db/mgi_rdf/MGI:95305
• transgene insertion 4, Pradip Roy-Burman
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388169

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Eif4e<tm1.1Lfur>/Eif4e<tm1.1Lfur>,Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(Pbsn-cre)4Prb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm2.1Ppp>|Tg(Pbsn-cre)4Prb|Eif4e<tm1.1Lfur>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002052

文献

http://purl.org/net/cito/citesAsAuthority

• Luc. Furic, et.al., eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20679199