decreased tumor incidence_Suds3<tm1.1Rdp>/Suds3<+>,Trp53<tm1Tyj>/Trp53<+>

http://metadb.riken.jp/0002052I129S2SvPasC57BL6FVBSuds3tm11RdpSuds3Trp53tm1TyjTrp53Suds3Suds3tm11RdpTrp53Trp53tm1Tyj

decreased tumor incidence_Suds3<tm1.1Rdp>/Suds3<+>,Trp53<tm1Tyj>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• suppressor of defective silencing 3 homolog (S. cerevisiae)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1919204

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Suds3<tm1.1Rdp>/Suds3<+>,Trp53<tm1Tyj>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Suds3<+>|Suds3<tm1.1Rdp>|Trp53<+>|Trp53<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002052

文献

http://purl.org/net/cito/citesAsAuthority

• G. David, et.al., Haploinsufficiency of the mSds3 chromatin regulator promotes chromosomal instability and cancer only upon complete neutralization of p53., Oncogene, 2006, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16767157