decreased tumor incidence_Apc<Min>/Apc<+>,Col1a1<tm1(CAG-Sirt1)Dsin>/Col1a1<+>,Tg(Vil1-cre)997Gum/0

http://metadb.riken.jp/0002052I129S4SvJaeC57BL6C57BL6JSJLApcMinApcCol1a1tm1CAGSirt1DsinCol1a1TgVil1cre997Gum0Col1a1ApcMinApcCol1a1tm1CAGSirt1DsinTgVil1cre997Gum

decreased tumor incidence_Apc<Min>/Apc<+>,Col1a1<tm1(CAG-Sirt1)Dsin>/Col1a1<+>,Tg(Vil1-cre)997Gum/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 997, Deborah L Gumucio
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446957
• collagen, type I, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88467
• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<Min>/Apc<+>,Col1a1<tm1(CAG-Sirt1)Dsin>/Col1a1<+>,Tg(Vil1-cre)997Gum/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Col1a1<+>|Apc<Min>|Apc<+>|Col1a1<tm1(CAG-Sirt1)Dsin>|Tg(Vil1-cre)997Gum

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002052

文献

http://purl.org/net/cito/citesAsAuthority

• Ron. Firestein, et.al., The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth., PloS one, 2008, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/18414679