decreased tumor incidence_Cav1<tm1Mls>/Cav1<tm1Mls>,Tg(TRAMP)8247Ng/0

http://metadb.riken.jp/0002052I129SvC57BL6SJLCav1tm1MlsCav1tm1MlsTgTRAMP8247Ng0Cav1tm1MlsTgTRAMP8247Ng

decreased tumor incidence_Cav1<tm1Mls>/Cav1<tm1Mls>,Tg(TRAMP)8247Ng/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 8247, Norman M Greenberg
  http://metadb.riken.jp/db/mgi_rdf/MGI:2680364
• caveolin 1, caveolae protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:102709

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cav1<tm1Mls>/Cav1<tm1Mls>,Tg(TRAMP)8247Ng/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cav1<tm1Mls>|Tg(TRAMP)8247Ng

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased tumor incidence
  http://purl.obolibrary.org/obo/MP_0002052

文献

http://purl.org/net/cito/citesAsAuthority

• Terence M. Williams, et.al., Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice., The Journal of biological chemistry, 2005, 280
  http://rdf.ncbi.nlm.nih.gov/pubmed/15802273