decreased incidence of induced tumors_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>

http://metadb.riken.jp/0002053I129P2OlaHsd129S4SvJaeKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnTrp53tm1BrnKrastm4TyjKras

decreased incidence of induced tumors_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brn>|Kras<tm4Tyj>|Kras<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased incidence of induced tumors
  http://purl.obolibrary.org/obo/MP_0002053

文献

http://purl.org/net/cito/citesAsAuthority

• Etienne. Meylan, et.al., Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma., Nature, 2009, 462
  http://rdf.ncbi.nlm.nih.gov/pubmed/19847165