seizures_Pten<tm1Rdp>/Pten<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(GFAP-cre)25Mes/0

http://metadb.riken.jp/0002064I129P2OlaHsd129S6SvEvTacC57BL6FVBNPtentm1RdpPtenTrp53tm1BrnTrp53tm1BrnTgGFAPcre25Mes0Trp53tm1BrnPtentm1RdpPtenTgGFAPcre25Mes

seizures_Pten<tm1Rdp>/Pten<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(GFAP-cre)25Mes/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 25, Albee Messing
  http://metadb.riken.jp/db/mgi_rdf/MGI:2179047

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Rdp>/Pten<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(GFAP-cre)25Mes/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brn>|Pten<tm1Rdp>|Pten<+>|Tg(GFAP-cre)25Mes

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• seizures
  http://purl.obolibrary.org/obo/MP_0002064

文献

http://purl.org/net/cito/citesAsAuthority

• Hongwu. Zheng, et.al., p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation., Nature, 2008, 455
  http://rdf.ncbi.nlm.nih.gov/pubmed/18948956