seizures_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(Camk2a-cre)1Gsc/0

http://metadb.riken.jp/0002064I129P2OlaHsd129S7SvEvBrdC57BL6FVBNGna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgCamk2acre1Gsc0Gna11tm1SoffTgCamk2acre1GscGnaqtm2Soff

seizures_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(Camk2a-cre)1Gsc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• guanine nucleotide binding protein, alpha 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:95766
• transgene insertion 1, Gunther Schutz
  http://metadb.riken.jp/db/mgi_rdf/MGI:2181421
• guanine nucleotide binding protein, alpha q polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:95776

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(Camk2a-cre)1Gsc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gna11<tm1Soff>|Tg(Camk2a-cre)1Gsc|Gnaq<tm2Soff>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• seizures
  http://purl.obolibrary.org/obo/MP_0002064

文献

http://purl.org/net/cito/citesAsAuthority

• Nina. Wettschureck, et.al., Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation., Molecular and cellular biology, 2006, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/16847339