seizures_Scn1a<tm1.1Aesc>/Scn1a<+>

http://metadb.riken.jp/0002064I129X1SvJC57BL6JSJLScn1atm11AescScn1aScn1aScn1atm11Aesc

seizures_Scn1a<tm1.1Aesc>/Scn1a<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sodium channel, voltage-gated, type I, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:98246

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Scn1a<tm1.1Aesc>/Scn1a<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Scn1a<+>|Scn1a<tm1.1Aesc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• seizures
  http://purl.obolibrary.org/obo/MP_0002064

文献

http://purl.org/net/cito/citesAsAuthority

• Melinda S. Martin, et.al., Altered function of the SCN1A voltage-gated sodium channel leads to gamma-aminobutyric acid-ergic (GABAergic) interneuron abnormalities., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20100831