increased circulating insulin level_Lep<ob>/Lep<ob>

http://metadb.riken.jp/0002079B6CgLepobJLepobLepobLepob

increased circulating insulin level_Lep<ob>/Lep<ob>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• leptin
  http://metadb.riken.jp/db/mgi_rdf/MGI:104663

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lep<ob>/Lep<ob>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lep<ob>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Lep<ob>/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating insulin level
  http://purl.obolibrary.org/obo/MP_0002079

文献

http://purl.org/net/cito/citesAsAuthority

• F. Dong, et.al., Impaired cardiac contractile function in ventricular myocytes from leptin-deficient ob/ob obese mice., The Journal of endocrinology, 2006, 188
  http://rdf.ncbi.nlm.nih.gov/pubmed/16394172
• D L. Coleman, et.al., The influence of genetic background on the expression of the obese (Ob) gene in the mouse., Diabetologia, 1973, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/4588246
• Eiichi. Hinoi, et.al., The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity., The Journal of cell biology, 2008, 183
  http://rdf.ncbi.nlm.nih.gov/pubmed/19103808
• Maria. Sakkou, et.al., A role for brain-specific homeobox factor Bsx in the control of hyperphagia and locomotory behavior., Cell metabolism, 2007, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/17550780