increased circulating insulin level_Appl1<Gt(RRS819)Byg>/Appl1<Gt(RRS819)Byg>

http://metadb.riken.jp/0002079I129P2OlaHsdC57BL6Appl1GtRRS819BygAppl1GtRRS819BygAppl1GtRRS819Byg

increased circulating insulin level_Appl1<Gt(RRS819)Byg>/Appl1<Gt(RRS819)Byg>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1920243

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Appl1<Gt(RRS819)Byg>/Appl1<Gt(RRS819)Byg>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Appl1<Gt(RRS819)Byg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating insulin level
  http://purl.obolibrary.org/obo/MP_0002079

文献

http://purl.org/net/cito/citesAsAuthority

• Jiyoon. Ryu, et.al., APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor., Cell reports, 2014, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/24813896