increased circulating insulin level_Lep<ob>/Lep<ob>,Serpine1<tm1Mlg>/Serpine1<tm1Mlg>

http://metadb.riken.jp/0002079I129S2SvPasC57BL6LepobLepobSerpine1tm1MlgSerpine1tm1MlgLepobSerpine1tm1Mlg

increased circulating insulin level_Lep<ob>/Lep<ob>,Serpine1<tm1Mlg>/Serpine1<tm1Mlg>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• leptin
  http://metadb.riken.jp/db/mgi_rdf/MGI:104663
• serine (or cysteine) peptidase inhibitor, clade E, member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97608

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lep<ob>/Lep<ob>,Serpine1<tm1Mlg>/Serpine1<tm1Mlg>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lep<ob>|Serpine1<tm1Mlg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating insulin level
  http://purl.obolibrary.org/obo/MP_0002079

文献

http://purl.org/net/cito/citesAsAuthority

• K. Schäfer, et.al., Disruption of the plasminogen activator inhibitor 1 gene reduces the adiposity and improves the metabolic profile of genetically obese and diabetic ob/ob mice., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/11481248