increased circulating insulin level_Insr<tm1Khn>/Insr<tm1Dac>,Tg(Ckmm-cre)5Khn/0

http://metadb.riken.jp/0002079I129S4SvJaeC57BL6JFVBInsrtm1KhnInsrtm1DacTgCkmmcre5Khn0Insrtm1DacInsrtm1KhnTgCkmmcre5Khn

increased circulating insulin level_Insr<tm1Khn>/Insr<tm1Dac>,Tg(Ckmm-cre)5Khn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96575
• transgene insertion 5, C Ronald Kahn
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182093

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Insr<tm1Khn>/Insr<tm1Dac>,Tg(Ckmm-cre)5Khn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Insr<tm1Dac>|Insr<tm1Khn>|Tg(Ckmm-cre)5Khn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6J * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating insulin level
  http://purl.obolibrary.org/obo/MP_0002079

文献

http://purl.org/net/cito/citesAsAuthority

• J C. Brüning, et.al., A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance., Molecular cell, 1998, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/9844629