premature death_Kras<tm4Tyj>/Kras<+>,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>

http://metadb.riken.jp/0002083B6129Krastm4TyjTgfbr2tm12HlmKrastm4TyjKrasTgfbr2tm12HlmTgfbr2tm12HlmTgfbr2tm12HlmKrastm4TyjKras

premature death_Kras<tm4Tyj>/Kras<+>,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• transforming growth factor, beta receptor II
  http://metadb.riken.jp/db/mgi_rdf/MGI:98729

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Tgfbr2<tm1.2Hlm>/Tgfbr2<tm1.2Hlm>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tgfbr2<tm1.2Hlm>|Kras<tm4Tyj>|Kras<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.129-Kras<tm4Tyj> Tgfbr2<tm1.2Hlm>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• Alain C. Borczuk, et.al., Progression of human bronchioloalveolar carcinoma to invasive adenocarcinoma is modeled in a transgenic mouse model of K-ras-induced lung cancer by loss of the TGF-β type II receptor., Cancer research, 2011, 71
  http://rdf.ncbi.nlm.nih.gov/pubmed/21911454