premature death_Brca1<tm2Mak>/Brca1<tm2Mak>,Tg(Lck-cre)548Jxm/?,Trp53<tm1Brd>/Trp53<tm1Brd>

http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6CBABrca1tm2MakBrca1tm2MakTgLckcre548JxmTrp53tm1BrdTrp53tm1BrdTgLckcre548JxmBrca1tm2MakTrp53tm1Brd

premature death_Brca1<tm2Mak>/Brca1<tm2Mak>,Tg(Lck-cre)548Jxm/?,Trp53<tm1Brd>/Trp53<tm1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• breast cancer 1, early onset
  http://metadb.riken.jp/db/mgi_rdf/MGI:104537
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 548, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176198

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Brca1<tm2Mak>/Brca1<tm2Mak>,Tg(Lck-cre)548Jxm/?,Trp53<tm1Brd>/Trp53<tm1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Lck-cre)548Jxm|Brca1<tm2Mak>|Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• John Peter. McPherson, et.al., Collaboration of Brca1 and Chk2 in tumorigenesis., Genes & development, 2004, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/15131084