premature death_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Wrn<tm1Lgu>/Wrn<tm1Lgu>

http://metadb.riken.jp/0002083I129S2SvPasBALBcTrp53tm1TyjTrp53tm1TyjWrntm1LguWrntm1LguTrp53tm1TyjWrntm1Lgu

premature death_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Wrn<tm1Lgu>/Wrn<tm1Lgu>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• Werner syndrome RecQ like helicase
  http://metadb.riken.jp/db/mgi_rdf/MGI:109635

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Tyj>/Trp53<tm1Tyj>,Wrn<tm1Lgu>/Wrn<tm1Lgu>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Tyj>|Wrn<tm1Lgu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * BALB/c

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• D B. Lombard, et.al., Mutations in the WRN gene in mice accelerate mortality in a p53-null background., Molecular and cellular biology, 2000, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/10757812