premature death_Ccr2<tm1Ifc>/Ccr2<tm1Ifc>,Tg(APPSWE)2576Kha/0

http://metadb.riken.jp/0002083I129S4SvJaeC57BL6SJLCcr2tm1IfcCcr2tm1IfcTgAPPSWE2576Kha0Ccr2tm1IfcTgAPPSWE2576Kha

premature death_Ccr2<tm1Ifc>/Ccr2<tm1Ifc>,Tg(APPSWE)2576Kha/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• chemokine (C-C motif) receptor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:106185
• transgene insertion 2576, Karen Hsiao Ashe
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385632

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ccr2<tm1Ifc>/Ccr2<tm1Ifc>,Tg(APPSWE)2576Kha/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ccr2<tm1Ifc>|Tg(APPSWE)2576Kha

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• Joseph. El Khoury, et.al., Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease., Nature medicine, 2007, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/17351623