premature death_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(NES-TVA)J12Ech/0

http://metadb.riken.jp/0002083I129SvC57BL6FVBNSJLCdkn2atm1RdpCdkn2atm1RdpTgNESTVAJ12Ech0TgNESTVAJ12EchCdkn2atm1Rdp

premature death_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(NES-TVA)J12Ech/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion J12, Eric C Holland
  http://metadb.riken.jp/db/mgi_rdf/MGI:3619221
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(NES-TVA)J12Ech/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(NES-TVA)J12Ech|Cdkn2a<tm1Rdp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• E. Tchougounova, et.al., Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma., Oncogene, 2007, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/17438529
• Lynette M. Moore, et.al., IGFBP2 is a candidate biomarker for Ink4a-Arf status and a therapeutic target for high-grade gliomas., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19805356