premature death_Mapk1<tm1.1Hed>/Mapk1<tm1.1Hed>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>

http://metadb.riken.jp/0002083I129SvMapk1tm11HedMapk1tm11HedMapk3tm1GpgMapk3tm1GpgPolr2atm1creERT2BbdPolr2atm1creERT2BbdMapk1tm11HedPolr2atm1creERT2BbdMapk3tm1Gpg

premature death_Mapk1<tm1.1Hed>/Mapk1<tm1.1Hed>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• polymerase (RNA) II (DNA directed) polypeptide A
  http://metadb.riken.jp/db/mgi_rdf/MGI:98086
• mitogen-activated protein kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346858
• mitogen-activated protein kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346859

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mapk1<tm1.1Hed>/Mapk1<tm1.1Hed>,Mapk3<tm1Gpg>/Mapk3<tm1Gpg>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<tm1(cre/ERT2)Bbd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mapk1<tm1.1Hed>|Polr2a<tm1(cre/ERT2)Bbd>|Mapk3<tm1Gpg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• Rafael B. Blasco, et.al., c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma., Cancer cell, 2011, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/21514245