premature death_Cfl2<tm1Itl>/Cfl2<tm1Itl>,Tg(Ckmm-cre)5Khn/0

http://metadb.riken.jp/0002083IC57BL6C57BL6NTacFVBNCfl2tm1ItlCfl2tm1ItlTgCkmmcre5Khn0TgCkmmcre5KhnCfl2tm1Itl

premature death_Cfl2<tm1Itl>/Cfl2<tm1Itl>,Tg(Ckmm-cre)5Khn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cofilin 2, muscle
  http://metadb.riken.jp/db/mgi_rdf/MGI:101763
• transgene insertion 5, C Ronald Kahn
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182093

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cfl2<tm1Itl>/Cfl2<tm1Itl>,Tg(Ckmm-cre)5Khn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ckmm-cre)5Khn|Cfl2<tm1Itl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6NTac * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• Pankaj B. Agrawal, et.al., Normal myofibrillar development followed by progressive sarcomeric disruption with actin accumulations in a mouse Cfl2 knockout demonstrates requirement of cofilin-2 for muscle maintenance., Human molecular genetics, 2012, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/22343409