premature death_Tg(Lck-Notch3)#Issc/0

http://metadb.riken.jp/0002083IC57BL6DBA2TgLckNotch3Issc0TgLckNotch3Issc

premature death_Tg(Lck-Notch3)#Issc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Isabella Screpanti
  http://metadb.riken.jp/db/mgi_rdf/MGI:4843438

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Lck-Notch3)#Issc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Lck-Notch3)#Issc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• premature death
  http://purl.obolibrary.org/obo/MP_0002083

文献

http://purl.org/net/cito/citesAsAuthority

• Maria Pia. Felli, et.al., PKC theta mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia., Oncogene, 2005, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/15592506
• D. Bellavia, et.al., Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice., The EMBO journal, 2000, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/10880446