abnormal lipid homeostasis_Akt2<tm1.2Mbb>/Akt2<tm1.2Mbb>,Lep<ob>/Lep<ob>,Tg(Alb1-cre)1Khk/0

http://metadb.riken.jp/0002118I129P2OlaHsd129S4SvJaeSorC57BL6SJLAkt2tm12MbbAkt2tm12MbbLepobLepobTgAlb1cre1Khk0TgAlb1cre1KhkAkt2tm12MbbLepob

abnormal lipid homeostasis_Akt2<tm1.2Mbb>/Akt2<tm1.2Mbb>,Lep<ob>/Lep<ob>,Tg(Alb1-cre)1Khk/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• leptin
  http://metadb.riken.jp/db/mgi_rdf/MGI:104663
• thymoma viral proto-oncogene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:104874
• transgene insertion 1, Klaus H Kaestner
  http://metadb.riken.jp/db/mgi_rdf/MGI:2661922

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Akt2<tm1.2Mbb>/Akt2<tm1.2Mbb>,Lep<ob>/Lep<ob>,Tg(Alb1-cre)1Khk/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb1-cre)1Khk|Akt2<tm1.2Mbb>|Lep<ob>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal lipid homeostasis
  http://purl.obolibrary.org/obo/MP_0002118

文献

http://purl.org/net/cito/citesAsAuthority

• Karla F. Leavens, et.al., Akt2 is required for hepatic lipid accumulation in models of insulin resistance., Cell metabolism, 2009, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/19883618