abnormal lipid homeostasis_Apoe<tm1(APOE*2)Mae>/Apoe<tm1(APOE*2)Mae>,Ldlr<tm1(LDLR)Mae>/Ldlr<+>

http://metadb.riken.jp/0002118I129P2OlaHsd129S6SvEvTacC57BL6Apoetm1APOE2MaeApoetm1APOE2MaeLdlrtm1LDLRMaeLdlrLdlrApoetm1APOE2MaeLdlrtm1LDLRMae

abnormal lipid homeostasis_Apoe<tm1(APOE*2)Mae>/Apoe<tm1(APOE*2)Mae>,Ldlr<tm1(LDLR)Mae>/Ldlr<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765
• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apoe<tm1(APOE*2)Mae>/Apoe<tm1(APOE*2)Mae>,Ldlr<tm1(LDLR)Mae>/Ldlr<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ldlr<+>|Apoe<tm1(APOE*2)Mae>|Ldlr<tm1(LDLR)Mae>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal lipid homeostasis
  http://purl.obolibrary.org/obo/MP_0002118

文献

http://purl.org/net/cito/citesAsAuthority

• C. Knouff, et.al., Doubling expression of the low density lipoprotein receptor by truncation of the 3'-untranslated region sequence ameliorates type iii hyperlipoproteinemia in mice expressing the human apoe2 isoform., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11076954