abnormal definitive hematopoiesis_Col1a1<tm1(tetO-U2AF1*S34F)Mjwa>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/?

http://metadb.riken.jp/0002123I129S4SvJaeC57BL6Col1a1tm1tetOU2AF1S34FMjwaCol1a1GtROSA26Sortm1rtTAM2JaeCol1a1tm1tetOU2AF1S34FMjwaCol1a1GtROSA26Sortm1rtTAM2Jae

abnormal definitive hematopoiesis_Col1a1<tm1(tetO-U2AF1*S34F)Mjwa>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• collagen, type I, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88467

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col1a1<tm1(tetO-U2AF1*S34F)Mjwa>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Col1a1<tm1(tetO-U2AF1*S34F)Mjwa>|Col1a1<+>|Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal definitive hematopoiesis
  http://purl.obolibrary.org/obo/MP_0002123

文献

http://purl.org/net/cito/citesAsAuthority

• Cara Lunn. Shirai, et.al., Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo., Cancer cell, 2015, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/25965570