abnormal kidney physiology_Pkd1<tm1Gztn>/Pkd1<tm1Gztn>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0002136I129SSv129S7SvEvBrdC57BL6Pkd1tm1GztnPkd1tm1GztnGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorPkd1tm1Gztn

abnormal kidney physiology_Pkd1<tm1Gztn>/Pkd1<tm1Gztn>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• polycystic kidney disease 1 homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:97603
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pkd1<tm1Gztn>/Pkd1<tm1Gztn>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>|Gt(ROSA)26Sor<+>|Pkd1<tm1Gztn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/Sv * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal kidney physiology
  http://purl.obolibrary.org/obo/MP_0002136

文献

http://purl.org/net/cito/citesAsAuthority

• Thomas A. Natoli, et.al., Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models., Nature medicine, 2010, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/20562878