abnormal B cell differentiation_Igk-Eik<tm1Cgn>/Igk-Eik<tm1Cgn>

http://metadb.riken.jp/0002144EI129P2OlaHsdC57BL6orI129S2SvPasC57BL6IgkEiktm1CgnIgkEiktm1CgnIgkEiktm1Cgn

abnormal B cell differentiation_Igk-Eik<tm1Cgn>/Igk-Eik<tm1Cgn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin kappa chain, enhancer intronic
  http://metadb.riken.jp/db/mgi_rdf/MGI:1354193

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igk-Eik<tm1Cgn>/Igk-Eik<tm1Cgn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igk-Eik<tm1Cgn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S2/SvPas * C57BL/6)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal B cell differentiation
  http://purl.obolibrary.org/obo/MP_0002144

文献

http://purl.org/net/cito/citesAsAuthority

• Y R. Zou, et.al., Gene targeting in the Ig kappa locus: efficient generation of lambda chain-expressing B cells, independent of gene rearrangements in Ig kappa., The EMBO journal, 1993, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/8458339
• S. Takeda, et.al., Deletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in trans., The EMBO journal, 1993, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/8508766