abnormal B cell differentiation_Igh-J<tm1.1Lave>/Igh-J<tm1.1Lave>,Igk-J<tm1.1Lave>/Igk-J<tm1.1Lave>,Tg(BCL2)22Wehi/0

http://metadb.riken.jp/0002144IC57BL6JWehiSJLJWehiIghJtm11LaveIghJtm11LaveIgkJtm11LaveIgkJtm11LaveTgBCL222Wehi0IgkJtm11LaveIghJtm11LaveTgBCL222Wehi

abnormal B cell differentiation_Igh-J<tm1.1Lave>/Igh-J<tm1.1Lave>,Igk-J<tm1.1Lave>/Igk-J<tm1.1Lave>,Tg(BCL2)22Wehi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 22, Walter and Eliza Hall Institute of Medical Research
  http://metadb.riken.jp/db/mgi_rdf/MGI:3052829
• immunoglobulin heavy chain, joining region
  http://metadb.riken.jp/db/mgi_rdf/MGI:96461
• immunoglobulin kappa chain, joining region
  http://metadb.riken.jp/db/mgi_rdf/MGI:96497

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh-J<tm1.1Lave>/Igh-J<tm1.1Lave>,Igk-J<tm1.1Lave>/Igk-J<tm1.1Lave>,Tg(BCL2)22Wehi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igk-J<tm1.1Lave>|Igh-J<tm1.1Lave>|Tg(BCL2)22Wehi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6JWehi * SJL/JWehi

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal B cell differentiation
  http://purl.obolibrary.org/obo/MP_0002144

文献

http://purl.org/net/cito/citesAsAuthority

• Laurent. Verkoczy, et.al., Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls., Journal of immunology (Baltimore, Md. : 1950), 2011, 187
  http://rdf.ncbi.nlm.nih.gov/pubmed/21908739