abnormal T cell differentiation_Aire<tm1.1Doi>/Aire<tm1.1Doi>,Tg(Ins2-TFRC/OVA)296Wehi/0,Tg(TcraTcrb)425Cbn/0

http://metadb.riken.jp/0002145I129P2OlaHsdC57BL6Airetm11DoiAiretm11DoiTgIns2TFRCOVA296Wehi0TgTcraTcrb425Cbn0TgTcraTcrb425CbnTgIns2TFRCOVA296WehiAiretm11Doi

abnormal T cell differentiation_Aire<tm1.1Doi>/Aire<tm1.1Doi>,Tg(Ins2-TFRC/OVA)296Wehi/0,Tg(TcraTcrb)425Cbn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1338803
• transgene insertion 296, Walter and Eliza Hall Institute of Medical Research
  http://metadb.riken.jp/db/mgi_rdf/MGI:3578728
• transgene insertion 425, Frank Carbone
  http://metadb.riken.jp/db/mgi_rdf/MGI:3046085

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Aire<tm1.1Doi>/Aire<tm1.1Doi>,Tg(Ins2-TFRC/OVA)296Wehi/0,Tg(TcraTcrb)425Cbn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TcraTcrb)425Cbn|Tg(Ins2-TFRC/OVA)296Wehi|Aire<tm1.1Doi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal T cell differentiation
  http://purl.obolibrary.org/obo/MP_0002145

文献

http://purl.org/net/cito/citesAsAuthority

• Maureen A. Su, et.al., Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire., The Journal of clinical investigation, 2008, 118
  http://rdf.ncbi.nlm.nih.gov/pubmed/18414681